Cameos have often depicted the Virgin and Child, especially throughout the Roman Catholic religion. Tender images of the Virgin Mary with her son are among the most beloved in Christian art. Even early images from about the 6th century AD depict her gently cradling or supporting a haloed child or infant on her lap. Devotion to Mary in her dual role as the human mother of Jesus and a divine entity reached a peak in the 14th to 16th centuries, creating great demand for depictions of the mother and child. The term Madonna is Italian for “my lady” and was conferred as a title of respect or high rank, but came to be synonymous with the mother of the holy child and also with the physical representation or manifestation of the two. Small works of art depicting this theme were generally objects of personal worship and prayer intended for intimate use in a private setting, usually a home or a small chapel. Larger and more expansive scenes were produced for altars in public churches, often commissioned by a family or guild as an expression of devotion and an outward display of wealth. Over the centuries different themes emerged, but always with the mother and child as central figures in the scene. Reference: The National Gallery of Art